Field-Flow Fractionation

GF2000 Splitt FFF - Particle Fractionator

With the introduction of the GF2000 Postnova has launched a new type of Gravitational Splitt FFF. The GF2000 is the first true completely integrated and modular commercial G-Splitt including online optical particle detection. The machine can be used to separate, fractionate, purify and to characterize microparticles in one step. The attached PN3000 XPT detector allows determination of size and shape of the particle fractions eluting from the channel. The system features a broad separation range from 1 to 100 µm depending on sample nature and has the ability to separate different shaped particle fractions from each other. The GF2000 is clearly setting a new standard in the area of microparticle fractionation and marks a real break-through in Splitt science. The system is using Postnova's unique G-Splitt FFF channel which can be re-used and cleaned after operation. Special pumps deliver and control all necessary in- and outlet flows and the attached PN3000 XPT detector provides further information about the particle fractions via its powerful software.

GF2000 Splitt FFF - Particle Fractionator

AF2000 MultiFlow FFF - Universal Separator

The most Advanced Flow FFF Platform for Separation of Proteins, Macromolecules and Nanoparticles!
Professional Modular Platform
The new Postnova AF2000 MultiFlow FFF Series was invented to become the first professional modular Flow FFF platform available. It is completely integrated by the NovaFFF single software platform which runs the entire system from autosampler to detectors. The AF2000 Series incorporates the combined solid know-how and the technologies from three decades of leadership in FFF. Due to its unique design, the AF2000 MultiFlow platform offers more flexibility, higher robustness and better performance than any system before. The technology sets a new standard in the area of Flow FFF and marks a real break-through in FFF science and therefore naturally has become the leading Flow FFF solution for many scientists around the world.
Universal Flexible Separator
The AF2000 Series platform is based on the Flow FFF principle, using a crossflow field as driving force for the separation. The samples, which are affected by this field, are separated by their Dynamic Diffusion on the basis of the molar mass or particle size. The AF2000 can be run with different eluents, at various temperature conditions and is able to employ various channel dimensions and principles. The same system can be used for running planar Asymmetric Flow FFF (AF4) channels or circular HollowFiber Flow FFF (HF5) channels. Therefore, the AF2000 MultiFlow can be easily used for separation of a broad range of different samples from the area of Biopharmaceuticals, Food-Agro-Cosmetics, Environmental, Chemicals and Nanotechnology. The MultiFlow FFF is ideal for the characterization of proteins, antibodies, aggregates, vaccines, liposomes, nanoparticles and natural or synthetic macromolecules. Because of its great flexibility, the AF2000 MultiFlow FFF can be employed as a Universal Separator for many kind of analyte systems and is a secure investment also for new upcoming samples and future project demands.
AF2000 AT - Standard Ambient Temp Flow FFF
The AF2000 AT is a non-temperature controlled economical Flow FFF which is ideal for the use in general level research in universities, companies and public scientific centers. It is available as aqueous metal-free, stainless steel and multisolvent version and can be run with a broad range of aqueous and organic solvents. Planar Asymmetric Flow FFF (AF4) and circular HollowFiber Flow FFF (HF5) channels can used at the same time. Various detection principles such as UV-Absorbance (UV), Refractive Index (RI), Multi-Angle Light Scattering (MALS), Dynamic Light Scattering (DLS) and Inductively Coupled Plasma Mass Spectroscopy (ICP-MS) can be coupled easily. The AF2000 MT is a temperature controlled advanced Flow FFF system which is ideal for the use in higher level research in university and public research institutions as well as professional research and commercial-industrial applications in the area of product development, manufacturing and quality control. It is also available as aqueous metal-free, stainless steel and multisolvent version and can be run with a broad range of aqueous and organic solvents. Planar Asymmetric Flow FFF (AF4) and circular HollowFiber Flow FFF (HF5) channels can used at the same time. Various detection principles such as UV-Absorbance (UV), Refractive Index (RI), Multi-Angle Light Scattering (MALS), Dynamic Light Scattering (DLS) and Inductively Coupled Plasma Mass Spectroscopy (ICP-MS) can be coupled easily. Temperature control is not only available for the separation channel but also for the entire system, including the transfer capillaries between the various modules and detectors.
AF2000 HT - Top-Level High Temp Flow FFF
The AF2000 HT is a special temperature controlled top-level Flow FFF system which is ideal for the use in research, development and quality control of polyolefins and high temperature macromolecules in universities, public research institutions and industry. It is available as stainless steel version and can be run with organic solvents from ambient temperature up to high temperature conditions. Special planar Asymmetric Flow FFF (AF4) channels made from stainless steel and ceramics are exclusively employed for this conditions. Infrared (IR), Refractive Index (RI), Multi-Angle Light Scattering (MALS) and Viscometry (Visco) can be used as detection principles .
Advanced Flow FFF Detection
In order to enable the user to fully access this wide application range, the AF2000 MultiFlow is available in different unique versions. Various add-on modules, extra options and special FFF detectors are available, such as Refractive Index (RI), Multi-Angle Light Scattering (MALS) and Dynamic Light Scattering (DLS). All Postnova FFF modules and detectors have been especially developed for FFF and are perfectly optimized not only for the use with the AF2000 MultiFlow FFF but also for the other Postnova FFF versions. Additionally, the AF2000 Series has been designed for easy interfacing with existing high-end detection technologies from leading instrument suppliers so that the user can ideally integrate the Postnova FFF technology into the existing laboratory infrastructure in order to maximize efficiency and investment.

AF2000 MultiFlow FFF - Universal Separator

EAF2000 Electrical AF4

Simultaneous Electrical and Asymmetrical Flow FFF
Principle and Advantages of EAF4
The Postnova EAF4 Technology combines the principle of Electrical and Asymmetrical Flow FFF in just one system. Electric and Cross Flow Fields can now be applied in one FFF channel. This opens completely new routes for FFF separations which are based on particle size / molar mass and also on particle/molecule charge, providing additional sample information and adding a true second dimension of separation to Flow FFF. The new EAF2000 series is a powerful 2D FFF system which can be used either as traditional Asymmetric Flow FFF or alternatively as hybrid FFF system utilizing both separation forces in the same channel simultaneously. This allows particle size and molar mass separations induced by the cross flow field and on top of this also charge separations by electrophoretic mobility induced by the electric field. Traditional Flow FFF separations typically provide particle size or molar mass distributions as final result. Now, with the advent of the EAF2000 any of these particle size and molar mass distributions can be further differentiated and transformed into a particle size or molar mass vs. charge distribution. This allows identifying charge heterogeneities which might be present inside the different size and molar mass fractions. As particle and molecule charge plays a primary role in many applications, such as protein aggregation, polymer flocculation, particle agglomeration and also in pharmaceutical formulations in general, the new EAF2000 opens completely new ways for a significantly better understanding of these phenomena and will quickly help to establish more efficient product development and QC processes.
Independent Determination of Zetapotential
The new Postnova EAF4 technology is also designed in such a way that it allows the determination of the Zetapotential of the analytes under investigation. This can be done independently from other established techniques and systems such as the industry standard Malvern Zetasizer Nano. This makes the EAF2000 a powerful tool which perfectly complements any existing technique for Zetapotential determination and adds great value to any lab active in biopharma, nanoparticle and polymer research.

EAF2000 Electrical AF4

SC2000 Modular SEC system

The Advanced Modular SEC Platform for Separation & Characterisation of Polymers, Proteins and Polysaccharides
Professional Modular System
The new Postnova SC2000 Modular SEC system offers unrivalled flexibility in Advanced SEC/GPC analysis. It is the first truly modular multi-detector SEC system available allowing flexible access to a wide range of applications. The system incorporates state-of-the-art detection technologies including light scattering (MALS > multi-angle light scattering) for absolute molecular weight and Viscosity detection for structural and conformational data. Many other detector and accessory options and combinations are available to build a system uniquely tailored to your application requirements, with the benefit of modularity to allow easy future expansion. In addition, the SC2000 can be further expanded to include FFF modules to widen the application range and allow both SEC and FFF separations to be carried out on the same sample within one instrument platform.

Postnova has drawn on over three decades of cutting-edge separations leadership to design a solid stable SEC platform for you to achieve maximum success with your applications.

SC2000 Modular SEC system

CF2000 Centrifugal FFF - Particle Separator

The most Advanced System for High Resolution Separation and Fractionation of Nanoparticles!
Principle and Advantages of CF3
The new advanced Postnova CF2000 Series was developed to become the first professional modular Centrifugal FFF system available. It is completely controlled by the NovaFFF single software platform which runs the entire system from autosampler to detectors. The CF2000 Centrifugal FFF incorporates the combined proven know-how and the technologies from three decades of leadership in FFF. Due to its unique design, the CF2000 Centrifugal FFF system offers more flexibility, higher robustness and better performance than traditional particle sizer systems. The CF2000 allows high resolution particle separation and sizing at the same time and consequently sets a complete new standard and offers a real alternative to traditional particle characterization techniques.
Broad Separation Range
The CF2000 system has a wide separation range and is able to separate smaller species, such as proteins and polymers, from larger particles in one run with high resolution. The system is ideal for nanoparticles and is also suitable for the microparticle range. Typical samples for the CF2000 Centrifugal FFF are latex, silica, TiO2, ZnO, Ag and Au particles. But also sediment and various organic and inorganic particles from surface, ground and waste waters can be separated and further analyzed after fractionation. In contrast to traditional particle sizing techniques, which work in the batch mode, the Centrifugal FFF technique physically separates each particle fraction prior to sizing. This avoids numerous disadvantages of the batch techniques such as low size resolution, discrimination and underestimation of smaller by larger particles. Same as with Flow FFF no special sample treatment is necessary as they can be injected directly without filtration, allowing the characterization of quite complex particulate sample systems without alteration and damage.
Particle Size and Density Separation
The CF2000 Series system is based on the Centrifugal FFF principle using a centrifugal field as driving force for the separation. Particles affected by this field are separated by Dynamic Diffusion on the basis of both the Particle Size and Density. This unique feature allows the separation of different particle materials having the same particle size. The separation can be further optimized by the use of different eluents and various temperature programs. Therefore, the CF2000 can be ideally used for separation of complex particle samples in the area of Environmental, Food-Agro-Cosmetics and Nanomaterials.
Advanced Centrifugal FFF Detection
In order to enable the user to fully access this wide application range, the CF2000 Centrifugal FFF is available with various add-on modules and special FFF detectors, such as Refractive Index (RI), Multi-Angle Light Scattering (MALS) and Dynamic Light Scattering (DLS). All Postnova FFF modules and FFF detectors have been especially designed for FFF and been optimized not only for the use with the CF2000 Centrifugal FFF but also for the other Postnova FFF versions. Additionally, the CF2000 Series has been designed for easy interfacing with existing high-end detection technologies from leading instrument suppliers so that the user can ideally integrate the Postnova FFF technology into the existing laboratory infrastructure in order to maximize efficiency and investment.

CF2000 Centrifugal FFF - Particle Separator

TF2000 Thermal FFF - Polymer Separator

The most Advanced System for Separation of Natural and Synthetic Polymers and Gel Particles!
Professional Modular System
The new award winning Postnova TF2000 Thermal FFF Series was invented to become the first professional modular Thermal FFF system available. It is completely integrated by the NovaFFF single software platform which runs the entire system from autosampler to detectors. The TF2000 Series incorporates the combined solid know-how and the proven technologies from three decades of leadership in FFF. Due to its unique design the TF2000 Thermal FFF system offers more flexibility, higher robustness and better performance than traditional chromatographic systems. A separation column with stationary phase is not required anymore and consequently the TF2000 technology sets a complete new standard and offers a real alternative to column-based polymer characterization techniques.
Broad Separation Range
The TF2000 system has a wide separation range and is able to separate small and large molar masses with high resolution. This allows the separation of various polymers, such as starches, polystyrenes, polymethylmetacrylates, synthetic and natural rubbers as well as other elastomers. In contrast to traditional chromatographic separation techniques, such as GPC/SEC, no sample treatment is necessary as the samples can be injected without filtration. This allows the characterization of quite complex polymer samples without any potential alteration and damage. Also, Thermal FFF has no Size Exclusion limit and because of this fact even ultra-high molar mass, branched and cross-linked polymers as well as gels, aggregates and particles can be separated.
Molar Mass and Composition Separation
The TF2000 Series system is based on the Thermal FFF principle, using a temperature gradient as driving force for the separation. Polymers effected by this field show Thermal Diffusion which allows the separation by both the Molar Mass and Chemical Composition. This unique feature allows the separation of different polymer material having the same molar mass. The separation can be further optimized by the use of different eluents and various temperature programs. Therefore, the TF2000 can be ideally used for separation of complex polymer samples in the area of Petrochemical, Adhesives, Rubbers, Polymers and Nanomaterials.
Advanced Thermal FFF Detection
In order to enable the user to fully access this wide application range, the TF2000 Thermal FFF is available with various add-on modules and special FFF detectors, such as Refractive Index (RI), Multi-Angle Light Scattering (MALS) and Dynamic Light Scattering (DLS). All Postnova FFF modules and FFF detectors have been especially designed for FFF and optimized not only for the use with the TF2000 Thermal FFF but also for the other Postnova FFF versions. Additionally, the TF2000 Series has been designed for easy interfacing with existing high-end detection technologies from leading instrument suppliers, so that the user can ideally integrate the Postnova FFF technology into the existing laboratory infrastructure in order to maximize efficiency and investment.

TF2000 Thermal FFF - Polymer Separator

Contact Us

Home Footer
ilac a2la.png
imageedit_11_2896054645.png

Copyrights © Dr. Golik All rights reserved 2020

Dr. Golik