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TF2000 Thermal FFF - Polymer Separator


Postnova Analytics

Postnova Analytics

The most Advanced System for Separation of Natural and Synthetic Polymers and Gel Particles!
Professional Modular System
The new award winning Postnova TF2000 Thermal FFF Series was invented to become the first professional modular Thermal FFF system available. It is completely integrated by the NovaFFF single software platform which runs the entire system from autosampler to detectors. The TF2000 Series incorporates the combined solid know-how and the proven technologies from three decades of leadership in FFF. Due to its unique design the TF2000 Thermal FFF system offers more flexibility, higher robustness and better performance than traditional chromatographic systems. A separation column with stationary phase is not required anymore and consequently the TF2000 technology sets a complete new standard and offers a real alternative to column-based polymer characterization techniques.

Key Differences

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Separation of Polymers, Gels and Particles

The TF2000 allows the simultaneous separation, characterization and fractionation of polymers, gels and particles within one measurement. The channel is reusable and only needs to be cleaned from time to time. There is no consumable which needs to be replaced frequently.

Broad Separation Range

Other than in chromatography, the separation in Thermal FFF can also be performed for polymers from 1 kDa up to molar masses of 10E9 and more Da. No size exclusion effect is observed, making the TF2000 the ideal tool for the separation of large and ultra-large cross-linked polymers.

Gentle Separation Conditions

Because of the open channel and the absence of any stationary phase the separation can be performed under the absence of shear forces and stress to the macromolecule. Typical chromatography problems, such as filtering/adsorption effects, shear induced chain degradation and late elution effects can be avoided.

Broad Range of Eluents

Because of the absence of the stationary phase, nearly any kind of organic and even some aqueous liquids can be used in Thermal FFF. Only the thermal diffusion properties of the polymers under investigation need to be sufficiently strong in the given eluent. This allows to easily use also aggressive and otherwise difficult to use eluents such as DMSO for starch analysis etc. There is no need to add salt such as LiBr which is often essential in chromatography to avoid polymer interacting with stationary phases.

R&D as well as QC Capability

Because the TF2000 does not use any membrane and is a very robust and easy to use instrument it can be easily employed as a routine tool for QC analysis 24/7 directly integrated into the chemical manufacturing processes. The TF2000 can be remote controlled, meets and conforms with the most stringent international security regulations and offers a series of automatic security features to allow unattended use. Temperature, pressure, leak and gas sensors are constantly monitoring the system for reproducibly and stable operation even in rough production environments.

Flexibility & Interfaceability

The TF2000 series was developed to be used as Stand-Alone system or interfaced with existing chromatographic systems from various manufacturers. This gives the advantage that FFF and GPC/LC can be performed using the same set or detectors, providing 2D information.

Technical Specification

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General Sample Size and Molar Mass Range:

Polymers: 10 kDa-100 MDa
Particles: 10 nm-1000 nm

Analysis Time:

Typical 10-120 min, no software limitation

Channel Dimensions:

Volume: 1.14 mL
Length: 456 mm
Breadth: 20 mm
Thickness: 130 µm

Channel Flow Rates:

Typically 0.01-2.0 mL/min
(For different flow rates ask Postnova)

Carrier Liquids:

Compatible with most organic solvent systems
(For aqueous solvents ask Postnova)


UV, RI, laser light scattering, fluorescence detection and more; multiple detectors in-line possible
(For details ask Postnova)

Thermal-Field Strength:

Maximum ΔT up to 120°C
Hot wall maximum: 180°C
Cold wall maximum: 60°C
(THF, 220 V, coolant water at 20°C, 12 L/min)

Temperature Control:

PC controlled for accurate, constant and programmed field options

Channel Pressure:

Up to 250 psi (approx. 14 bar) to pressurize the channel for any analysis at higher temperatures

System Requirements:

220-230 V, 50/60 Hz; 12 A for basic set-up
max. power consumption 3.5 kW
Coolant water at 20°C, 12 L/min, max. 2 bar
PC will  be supplied by Postnova, Windows English
(For details ask Postnova)

System Software:

NovaFFF TF2000


Rugged reuseable channel with no special maintenance required

Injection Volume:

1-1000 µL
Standard 20 µL
optional > 1000 µL

Injected Sample Mass:

Up to 500 µg and more; depending on sample characteristics; Typical injection mass 20-100 µg

Injection Method:

Via Rheodyne© manual injection valve or autosampler with different options

TF2000 Thermal FFF - Polymer Separator


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