Zetasizer AT


Malvern Panalytical

Malvern Panalytical

Zetasizer AT On-line particle size analyzer for nano-scale processes The Zetasizer AT brings the industry leading Dynamic Light Scattering (DLS) technology of the Zetasizer Nano to the process development and manufacturing arena, enabling real time monitoring of nanoscale particle processes on-line.

Key Differences

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The Zetasizer AT combines Malvern Panalytical's industry leading Dynamic Light Scattering (DLS) technology with two decades of expertise in design and automation of process interfaces for analytical instrumentation.

The Zetasizer AT is a fully-automated nanoparticle characterization system, delivering lab quality results on-line and in a timely manner for process optimization.

  • Ability to monitor processes involving nanoscale particles or droplets in real time e.g. homogenization

  • Ability to track changes in particle size with time and determine when the end point is reached

  • Automated sampling system facilitates sample extraction, degassing and dilution to the required concentration minimizing operator input

  • Sampling system designed to minimize sample consumption

  • Easy transfer of laboratory DLS methods to on-line system

  • Utilizes Malvern's Universal Interface for system integrators (Malvern Link II)

How it works

An automated sample preparation system utilizes high precision pumps and flow control valves to extract a sample out of a process pipe or vessel and dilute it to the required concentration. The sample is then degassed and pumped through the analyzer’s flow cell. After analysis the sample is discharged and the cycle repeats. Results are immediately available on the screen of the system computer and can be linked to plant SCADA or LIMS system.


Malvern Link II software controls every aspect of the sampling, dilution and degassing steps using Standard Operating Procedures (SOPs).

The Zetasizer AT also allows easy batch measurements of samples from other areas in the process, effectively doubling as a laboratory system.

Technical Specification

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Measurement range: 1nm – 1 micron* (diameter) (0.3nm – 10 microns*  at-line)

Measurement principle: Dynamic Light Scattering

Accuracy: Better than +/-2% on NIST traceable latex standards

Precision / Repeatability: Better than +/-2% on NIST traceable latex standards

Sensitivity: 0.1mg/mL (Lysozyme)

Sample Interface: 1/16" OD (0.040" ID) or 1/8" OD (1/16" ID) tube

Pressure: 0 - 3 Bar (0- 44 psi) at sample inlet.

Temperature: 0 – 90 °C (flow cell only)

Minimum sample volume: 4ml (application dependent)

Dilution: up to 1:50 / infinite (application dependent)

Power: 110-240VAC, 6A max, 50-60Hz

Compressed Air for optics purge (optional): 2-8 Bar (29-116 psi) per ISO8573-1:2010 [1.7.2]

Ingress Protection (IP) rating: IP54

Dimensions (W, D, H): 98 x 66 x 95 cm (38.6 x 26 x 37.4 inch)

Weight: 120.5 kg (266 lb)

Conforms to: 

  • Low Voltage Directive 2006/95/EC

  • EMC Directive 2004/108/EC

  • Pressure Equipment Directive 97/23/EC

  • BS EN 61010-1:2010     BS EN 60204-1:2006 + A1:2009   BS EN 61326-1:2006 

  • CE marked

Zetasizer AT


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