Manual PMDI wasting is a tedious time consuming task that can result in repetitive stress injuries over time. Coupled with this risk, improper manual shaking and shake-to-fire intervals in testing can vary the delivered dose from 75% to 320% of label claim per actuation. Over or under-delivery of the delivered dose during a single actuation can change the total drug concentration, introduce variability, and impact final results.
The Kinaero™ High-Throughput Fire-Down System is a solution that precisely automates shaking and actuation of up to 10 devices simultaneously, ensuring uniform dose delivery for every shot through the life of the devices.
Designed to meet rigorous testing standards for orally inhaled and nasal drug products (OINDPs), SprayVIEW® Measurement Systems are the industry standard for measuring and analyzing the spray pattern and plume geometry produced by spray and aerosol generating devices.
These systems have been validated and are being used in development and production environments at leading pharmaceutical companies, CDO/CMO/CROs, device manufacturers, and regulatory agencies around the world.
Indizo is a fully walk away platform that automates the labor intensive and error-prone tasks of spraying, weighing, and sample collection for pump delivery and dose content uniformity testing for vertically and side-actuated nasal sprays .
Using Vereo® Actuator technology as its core engine and Viota® software for control and analysis, the system reduces out-of-specification results and manual inconsistencies with precise, repeatable actuation, offering a superior level of parameter control to mimic human usage.