Malvern Panalytical

NanoSight NS300 High resolution nanoparticle size and concentration data The Malvern Panalytical NanoSight NS300 Instrument provides an easy-to-use, reproducible platform for nanoparticle characterization. The NS300 allows rapid analysis of the size distribution and concentration of all types of nanoparticles from 0.01 - 1 µm in diameter, depending on the instrument configuration and sample type. With the ability to be supplied with interchangeable laser modules and the introduction of a motorized filter wheel means different fluorescent labels can be analyzed. Sample temperature is fully programmable through the Nanoparticle Tracking Analysis (NTA) software.

MicroCal PEAQ-DSC Gold standard protein stability analysis for research applications The MicroCal PEAQ-DSC system provides highly sensitive, easy-to-use microcalorimetry that helps reduce the time and cost associated with stability testing and comparability analysis. The MicroCal PEAQ-DSC is a manual instrument with a cleaning device, which can be upgraded to an automated version upon request. Data generated by the MicroCal PEAQ-DSC provides critical guidance for biopharmaceutical development in protein engineering, (pre)formulation development, process development, manufacturing change control and biosimilarity and biocomparability studies. The integrated software streamlines workflows, facilitates non-subjective data analysis, performance qualification and compliance with 21 CFR Part 11 and Annex 11 regulations, all delivering high integrity data and driving productivity in biopharmaceutical research.

NanoSight LM10 Entry level, manual system The Malvern Panalytical NanoSight LM10 instrument provides an easy-to-use, reproducible platform for nanoparticle characterization. The LM10 allows rapid and accurate analysis of the size distribution and concentration of all types of nanoparticles from 0.01 - 1 µm* in diameter, depending on the instrument configuration and sample type. *Sample and system configuration dependent

Insitec Dry The industrially robust, technologically proven process particle size analyzer. Engineered to withstand the rigors of the process environment, Insitec Dry particle size analyzers use laser diffraction technology to measure particles in the size range 0.1 to 2500 µm. Insitec Dry can be configured to suit practically every dry particulate process, delivering real-time monitoring and control.

Insitec Wet The industrially robust, technologically proven process particle size analyzer. Engineered to withstand the rigors of the process environment, Insitec Wet particle size analyzers use laser diffraction technology to measure particles in the size range 0.1 to 2500 µm in emulsions, suspensions and slurries. Insitec Wet can be configured to suit practically every wet particulate process, delivering real-time monitoring and control 24/7.

MicroCal PEAQ-ITC The Gold Standard for measuring affinity and stoichiometry The MicroCal PEAQ-ITC is a highly sensitive, low volume isothermal titration calorimeter for the label-free in solution study of biomolecular interactions. It delivers direct measurement of all binding parameters in a single experiment and can analyze weak to high affinity binders, using as little as 10µg sample. Semi-automated maintenance minimizes operator intervention and the system is upgradable to the fully automated MicroCal PEAQ-ITC Automated, making it ideal for laboratories where speed, sensitivity and the ability to accommodate higher workloads in the future are paramount.

Rapid, automated particle size and particle shape analysis Morphologi 4 provides detailed morphological descriptions of particulate samples through static image analysis, enabling a greater understanding of both sample and process. It can equally be used as an R&D tool to investigate challenging applications and in automated QC analysis where generation of robust, user-independent results and validation are required.

NanoSight Sample Assistant Sample storage and walk-away NTA measurements The NanoSight Sample Assistant is a 96-well plate-based autosampler accessory with a bespoke software suite for SOP generation via an intuitive user interface for automated NTA measurements.

Spray particle and spray droplet size measurement
Malvern Panalytical's Spraytec laser diffraction system allows measurement of spray particle and spray droplet size distributions in real-time for more efficient product development of sprays and aerosols. It has been specifically designed to address the unique requirements for spray characterization and deliver robust, reproducible droplet size data.

Our entry-level Zetasizer does not compromise on features. The Zetasizer Lab incorporates Adaptive Correlation, M3-PALS and constant current zeta mode. The Zetasizer Lab also ships with ZS Xplorer, easy-to-use analytical software. ZS Xplorer offers instant feedback on data quality, and guidance on how to improve your results.

Zetasizer Ultra World’s most advanced light scattering system The new Zetasizer Ultra is our most advanced system for the measurement of particle and molecular size, particle charge and particle concentration, and represents the most intelligent and flexible instrument in the Zetasizer range. This flagship instrument enjoys all the benefits afforded by ZS Xplorer software, in terms of ease of use, analysis speed and data confidence, and also offers two unique measurement capabilities: Multi-Angle Dynamic Light Scattering (MADLS®) and Particle Concentration, to offer even greater insight into your samples.

Mastersizer 3000 Premier particle size analyzer The Mastersizer 3000 laser diffraction particle size analyzer delivers rapid, accurate particle size distributions for both wet and dry dispersions with the minimum of effort. Measuring over the nanometer to millimeter particle size ranges, it packs exceptional performance into the smallest of footprints, bringing operator-independent measurements that every user can rely on.

OMNISEC The world’s most advanced multi-detector GPC/SEC system Malvern Panalytical's OMNISEC is a Gel Permeation Chromatography (GPC) / Size Exclusion Chromatography (SEC) system for the measurement of absolute molecular weight, molecular size, intrinsic viscosity, branching and other parameters. It includes OMNISEC RESOLVE, the integrated GPC/SEC module, OMNISEC REVEAL, the integrated multi-detector module and OMNISEC software for the characterization of synthetic and natural polymers, and proteins.

Archimedes Sizing from Buoyant Mass Archimedes is an innovative instrument which uses the technique of resonant mass measurement to detect and accurately size and count particles in the size range 50nm to 5um*. Archimedes can distinguish different species from their buoyant mass is particularly useful when characterizing proteinaceous aggregates from contaminating silicon oil in biopharmaceutical preparations, in distinguishing bubbles from lipid micelles and contaminants in ultrasound contrast agents or protein from fat in dairy products.​ *Sample and sensor dependent

Insitec Spray The industrially robust, technologically proven process particle size analyzer for sprays and aerosols. Engineered to withstand the rigors of the process environment, Insitec Spray uses laser diffraction technology to measure droplets and dry particles from 0.1 µm to 2500µm. Capable of measuring even highly concentrated sprays and aerosols, Insitec Spray delivers real-time monitoring and control, 24/7.

MicroCal PEAQ-DSC Automated Gold standard protein stability analysis for the regulated environment The MicroCal PEAQ-DSC Automated system delivers high throughput, highly sensitive protein stability analysis with low sample consumption, in an automated, integrated platform for increased productivity. All cell filling and cleaning functions are fully automated for walk-away operation. Data generated by the MicroCal PEAQ-DSC Automated provide critical guidance for biopharmaceutical development in protein engineering, (pre)formulation development, process development, manufacturing change control and biosimilarity and biocomparability studies. Unattended operation enables 24-hour screening, while the integrated software streamlines workflows, facilitates non-subjective data analysis, performance qualification and compliance with 21 CFR Part 11 and Annex 11 regulations, all delivering high integrity data and driving productivity in biopharmaceutical research.

MicroCal PEAQ-ITC Automated Fully automated, hands free ITC for increased productivity The MicroCal PEAQ-ITC Automated is a configurable, low volume, highly sensitive isothermal titration calorimeter which offers the convenience of unattended operation. It delivers direct, label-free in solution measurement of all binding parameters in a single experiment. Applications include characterizing molecular interactions of small molecules, proteins, antibodies, nucleic acids, lipids and other biomolecules. It can also be used to measure enzyme kinetics

Rapid, automated, component-specific particle characterization in a single, integrated platform Morphologi 4-ID delivers detailed component-specific morphological descriptions of particulate blends through Morphologically-Directed Raman Spectroscopy (MDRS). This combines automated particle imaging with Raman spectroscopy in a single, integrated platform, providing the power to unlock complex particle characterization problems.

The Malvern Panalytical NanoSight syringe pump is available for all Malvern Panalytical NanoSight systems, enabling analysis in constant flow for improved sample statistics and measurement of photo-bleaching fluorescent samples.

Zetasizer AT On-line particle size analyzer for nano-scale processes The Zetasizer AT brings the industry leading Dynamic Light Scattering (DLS) technology of the Zetasizer Nano to the process development and manufacturing arena, enabling real time monitoring of nanoscale particle processes on-line.

Zetasizer Pro Enhanced speed and ease of use The new Zetasizer Pro is a robust and versatile system for the measurement of particle and molecular size and electrophoretic mobility and zeta potential of nanoparticles. It enables size measurements to be performed up to three times quicker, compared to previous models, accelerating sample throughput and freeing up operator and system time for other tasks